THIXOTROPY OF DIFFERENT CONCENTRATIONS OF MICROCRYSTALLINE CELLULOSE - SODIUM CARBOXYMETHYL CELLULOSE GELS

被引:16
|
作者
DOLZPLANAS, M [1 ]
ROLDANGARCIA, C [1 ]
HERRAEZDOMINGUEZ, JV [1 ]
BELDAMAXIMINO, R [1 ]
机构
[1] VALENCIA UNIV,FAC MED,DEPT PHYSIOL,E-46010 VALENCIA,SPAIN
关键词
D O I
10.1002/jps.2600800119
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
An extensive study is made of the rheologic behavior of microcrystalline cellulose:sodium carboxymethyl cellulose gels at six different concentrations (between 1 and 2.5% by weight). The thixotropy of these gels was analyzed in terms of agitation time, the duration of storage, concentration, and temperature; a semiempirical function was thus obtained providing thixotropic area as a function of these variables. The instantaneous variation rate in thixotropic area was defined, providing a better understanding of the rate of structural breakdown. Also, it is shown that after 5 min of agitation, the variation rate becomes negligible (approximately 0.7% of the initial value); this result is practically independent of the remaining variables.
引用
收藏
页码:75 / 79
页数:5
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