The influence of a diet rich in linseed oil (10% in weight) with a content of 61.2% of alpha-linolenic fatty acid on blood pressure and complex blood viscosity was investigated in spontaneously hypertensive rats. A decrease in blood pressure by 59 mm Hg was found compared to the age-matched, untreated control group. The viscous (eta") and elastic (eta") components of viscosity were also reduced at various shear rates (gamma). The same applies to the aggregation index, which is a measure of the aggregation tendency of red blood cells (RBC). Of course, the effects of blood viscosity cannot explain the observed degree of blood-pressure-lowering. Nevertheless, a decrease in the viscosity can improve the flow conditions in the microcirculation, which may lead to a better oxygen supply.
机构:
Univ Western Cape, Sch Pharm, Discipline Pharmacol, ZA-7535 Bellville, South AfricaUniv Western Cape, Sch Pharm, Discipline Pharmacol, ZA-7535 Bellville, South Africa
Raji, Ismaila A.
Mugabo, Pierre
论文数: 0引用数: 0
h-index: 0
机构:
Univ Western Cape, Sch Pharm, Discipline Pharmacol, ZA-7535 Bellville, South AfricaUniv Western Cape, Sch Pharm, Discipline Pharmacol, ZA-7535 Bellville, South Africa
Mugabo, Pierre
Obikeze, Kenechukwu
论文数: 0引用数: 0
h-index: 0
机构:
Univ Western Cape, Sch Pharm, Discipline Pharmacol, ZA-7535 Bellville, South AfricaUniv Western Cape, Sch Pharm, Discipline Pharmacol, ZA-7535 Bellville, South Africa