ANTIMICROBIAL ACTIVITY OF CRENATINE, AN ALKALOID SYNTHESIZED FROM INDOLE

被引：7

作者：

AJAYEOBA, EO

ADENIYI, BA

OKOGUN, JI

机构：

[1] UNIV IBADAN, COLL MED, DEPT PHARMACEUT MICROBIOL & CLIN PHARM, IBADAN, NIGERIA

[2] UNIV IBADAN, DEPT CHEM, IBADAN, NIGERIA

来源：

PHYTOTHERAPY RESEARCH | 1995年 / 9卷 / 01期

关键词：

CRENATINE; B-CARBOLINE ALKALOID; QUASSIA UNDULATA; ANTIMICROBIAL ACTIVITY;

D O I：

10.1002/ptr.2650090117

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Synthesized crenatine, a B-carboline alkaloid previously isolated from Quassia undulata (Guill & Perr) D. Dietr (Simaroubaceae) is shown to possess antibacterial but no antifungal activity. The activity was tested in vitro against seven Gram-positive, ten Gram-negative bacteria and a yeast at a concentration of 1 mg/mL. The compound was found to be more effective against Gram-positive than Gram-negative bacteria.

引用

页码：69 / 71

页数：3

共 9 条

[1]

AJAIYEOBA EO, 1993, IN PRESS NIG J NAT S

[2] SYNTHESIS AND PRELIMINARY PHARMACOLOGICAL STUDIES OF 1-ETHYL-BETA-CARBOLINE [J].