The effect of date palm fruit (Phoenix dactylifera L.) on the hormone 17-beta-estradiol in 7,12- dimethylbenz(alpha) anthracene-induced mammary cancer in rats

被引：4
|
作者：
Al-Sayyed, Hiba F. [1 ]
Takruri, Hamed R. [1 ]
Shomaf, Maha S. [2 ]
Al-Saleh, AbdulRahman [3 ]
机构：
[1] Univ Jordan, Fac Agr, Dept Nutr & Food Technol, Amman, Jordan
[2] Univ Jordan, Fac Med, Dept Pathol & Microbiol & Forens Med, Amman, Jordan
[3] Jordan Food & Drug Adm, Dept Food Labs, Div Food Microbiol, Labs, Amman, Jordan
来源：
MEDITERRANEAN JOURNAL OF NUTRITION AND METABOLISM | 2014年 / 7卷 / 01期
关键词：
Date palm fruit; 17-beta-estradiol; 7,12-dimethylbenz(alpha)anthracene-induced mammary cancer; sprague dawley rats;
D O I：
10.3233/MNM-140001
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The effect of date palm fruit feeding (to female Sprague-Dawley rats with 7,12-dimethylbenz(alpha) anthracene-induced mammary cancer) on the hormone 17-beta-estradiol concentration was compared to that of feeding soybean seeds and injection with two drugs (one preventive against and the other curative for 7,12-dimethylbenz(alpha) anthracene-induced mammary cancer i.e. tamoxifen and the hormone 17-beta-estradiol). The date palm fruit raised the hormone concentration significantly (p < 0.05). The hormone concentration was positively correlated with the palpable tumor latency, and negatively correlated with tumor incidence rate and multiplicity. It is concluded that the preventive effect of the date palm fruit against 7,12-dimethylbenz(alpha) anthraceneinduced mammary cancer is related to the effect on the hormone 17-beta-estradiol.
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页码：5 / 10
页数：6
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