BIOACTIVE MARINE METABOLITES .48. CINACHYROLIDE-A - A POTENT CYTOTOXIC MACROLIDE POSSESSING 2 SPIRO KETALS FROM MARINE SPONGE CINACHYRA SP

被引：137

作者：

FUSETANI, N

SHIMODA, K

MATSUNAGA, S

机构：

[1] Laboratory of Marine Biochemistry, Faculty of Agriculture, University of Tokyo, Tokyo 113, Bunkyo-ku

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1993年 / 115卷 / 10期

关键词：

D O I：

10.1021/ja00063a017

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly cytotoxic macrolide, cinachyrolide A, has been isolated from marine sponge Cinachyra sp. The gross structure was determined mainly by extensive 2D NMR experiments. The relative stereochemistry of the six oxane rings is proposed on the basis of NOESY data.

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页码：3977 / 3981

页数：5

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