THE TPR SNAP HELIX - A NOVEL PROTEIN REPEAT MOTIF FROM MITOSIS TO TRANSCRIPTION

被引：412
作者：
GOEBL, M
YANAGIDA, M
机构：
[1] INDIANA UNIV,SCH MED,WALTHER ONCOL CTR,INDIANAPOLIS,IN 46202
[2] KYOTO UNIV,FAC SCI,DEPT BIOPHYS,SAKYO KU,KYOTO 606,JAPAN
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 1991年 / 16卷 / 05期
关键词：
D O I：
10.1016/0968-0004(91)90070-C
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The recently discovered TPR gene family encodes a diverse group of proteins that function in mitosis, transcription, splicing, protein import and neurogenesis. These multi-domain proteins all contain tandemly arranged repeats of a 34-amino acid motif that are presumed to form helix-turn structures, each with a 'knob' and 'hole', acting as helix-associating domains.
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页码：173 / 177
页数：5
相关论文
共 25 条
  • [1] EXPANDING FAMILY
    BOGUSKI, MS
    SIKORSKI, RS
    HIETER, P
    GOEBL, M
    [J]. NATURE, 1990, 346 (6280) : 114 - 114
  • [2] THE PRODUCT OF THE PRP4 GENE OF S CEREVISIAE SHOWS HOMOLOGY TO BETA-SUBUNITS OF G-PROTEINS
    DALRYMPLE, MA
    PETERSENBJORN, S
    FRIESEN, JD
    BEGGS, JD
    [J]. CELL, 1989, 58 (05) : 811 - 812
  • [3] FONG HKW, 1986, P NATL ACAD SCI USA, V83, P2162, DOI 10.1073/pnas.83.7.2162
  • [4] METAPHASE CHROMOSOME STRUCTURE - INVOLVEMENT OF TOPOISOMERASE-II
    GASSER, SM
    LAROCHE, T
    FALQUET, J
    DELATOUR, EB
    LAEMMLI, UK
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 1986, 188 (04) : 613 - 629
  • [5] HARTWELL LH, 1985, GENETICS, V110, P381
  • [6] IMPORT OF PROTEINS INTO MITOCHONDRIA - NUCLEOTIDE-SEQUENCE OF THE GENE FOR A 70-KD PROTEIN OF THE YEAST MITOCHONDRIAL OUTER-MEMBRANE
    HASE, T
    RIEZMAN, H
    SUDA, K
    SCHATZ, G
    [J]. EMBO JOURNAL, 1983, 2 (12) : 2169 - 2172
  • [7] SNAP HELIX WITH KNOB AND HOLE - ESSENTIAL REPEATS IN S-POMBE NUCLEAR-PROTEIN NUC2+
    HIRANO, T
    KINOSHITA, N
    MORIKAWA, K
    YANAGIDA, M
    [J]. CELL, 1990, 60 (02) : 319 - 328
  • [8] A TEMPERATURE-SENSITIVE MUTATION OF THE SCHIZOSACCHAROMYCES-POMBE GENE NUC2+THAT ENCODES A NUCLEAR SCAFFOLD-LIKE PROTEIN BLOCKS SPINDLE ELONGATION IN MITOTIC ANAPHASE
    HIRANO, T
    HIRAOKA, Y
    YANAGIDA, M
    [J]. JOURNAL OF CELL BIOLOGY, 1988, 106 (04) : 1171 - 1183
  • [9] ISOLATION AND CHARACTERIZATION OF SCHIZOSACCHAROMYCES-POMBE CUT MUTANTS THAT BLOCK NUCLEAR DIVISION BUT NOT CYTOKINESIS
    HIRANO, T
    FUNAHASHI, S
    UEMURA, T
    YANAGIDA, M
    [J]. EMBO JOURNAL, 1986, 5 (11) : 2973 - 2979
  • [10] ICHO T, 1988, J BIOL CHEM, V263, P1467
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