THE TPR SNAP HELIX - A NOVEL PROTEIN REPEAT MOTIF FROM MITOSIS TO TRANSCRIPTION

被引：415

作者：

GOEBL, M

YANAGIDA, M

机构：

[1] INDIANA UNIV,SCH MED,WALTHER ONCOL CTR,INDIANAPOLIS,IN 46202

[2] KYOTO UNIV,FAC SCI,DEPT BIOPHYS,SAKYO KU,KYOTO 606,JAPAN

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1991年 / 16卷 / 05期

关键词：

D O I：

10.1016/0968-0004(91)90070-C

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The recently discovered TPR gene family encodes a diverse group of proteins that function in mitosis, transcription, splicing, protein import and neurogenesis. These multi-domain proteins all contain tandemly arranged repeats of a 34-amino acid motif that are presumed to form helix-turn structures, each with a 'knob' and 'hole', acting as helix-associating domains.

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页码：173 / 177

页数：5

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