SYNTHESIS OF 4-(2-CHLOROETHYL)-2,3-DIHYDRO[1,4]OXAZINO[2,3-B]QUINOLINE AND 4-(2-CHLOROETHYL)-2,3-DIHYDROPYRIDO[2,3-B][1,4]OXAZINE

被引:16
|
作者
ANDERSON, WK
DALVIE, DK
机构
[1] Department of Medicinal Chemistry, School of Pharmacy, State University of New York at Buffalo, Buffalo, New York
关键词
D O I
10.1002/jhet.5570300614
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The title compounds were synthesized from 3-[bis(2-hydroxyethyl)amino]quinolin-2(1H)-one 11a and 3-[bis(2-hydroxyethyl)amino]pyridin-2(1H)-one 18 respectively. The preparation involved a tandem chlorination/cyclization reaction.
引用
收藏
页码:1533 / 1536
页数:4
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