Synthesis of 3-(4-(Benzo[d]thiazol-2-yl)phenyl)-5-aryl-1,3,5-oxadiazinane-4-thiones and 1-(4-(Benzo[d]thiazol-2-yl)phenyl)-5-methyl-3-aryl-1,3,5-triazinane-2-thiones

被引：0

作者：

Uma, Pathki ^{[1
]}

Rajanna, Kamatala Chinna ^{[1
]}

Sriram, Yelike Hemanth ^{[1
]}

Premalatha, Akarapu ^{[1
]}

Saipraksh, Pondichery Kuppuswamy ^{[1
]}

机构：

[1] OU, Dept Chem, Hyderabad 500007, TS, India

来源：

SYNOPEN | 2018年 / 2卷 / 01期

关键词：

benzo[d]thiazols; isothiocyanates; thioureas;

D O I：

10.1055/s-0036-1591917

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In this investigation 4-(benzo[d]thiazol-2-yl)benzenamine was reacted with aryl isothiocyanates to give 1-(4-(benzo[d]thiazol-2yl)phenyl)-3-aryl thioureas 2, which were cyclized with acid to afford 3(4-(benzo[d]thiazol-2-yl)phenyl)-5-aryl-1,3,5-oxadiazinane-4-thiones 3. On the other hand, 1-(4-(benzo[d]thiazol-2-yl)phenyl)-5-methyl-3-aryl-1,3,5-triazinane-2-thiones 4 were obtained when compounds 2 were treated with amines.

引用

页码：30 / 35

页数：6

共 36 条

[1]

Akihama S, 1968, CHEM ABSTR, V68

[2] Microwave-assisted synthesis of triazones and 4-oxo-oxadiazinane in dry media [J].

Balalaie, S ;

Hashtroudi, MS ;

Sharifi, A .

JOURNAL OF CHEMICAL RESEARCH-S, 1999, (06) :392-393

[3]

Bradshaw TD, 2002, MOL CANCER THER, V1, P239

[4]

Brown H D, 1996, CHEM ABSTR, V65, P18593

[5] Riluzole - A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in amyotrophic lateral sclerosis [J].

Bryson, HM ;

Fulton, B ;

Benfield, P .

DRUGS, 1996, 52 (04) :549-563

[6]

CHARY MT, 1987, J INDIAN CHEM SOC, V64, P488

[7]

Deohate PP, 2005, INDIAN J CHEM B, V44, P638

[8]

Dickore K, 1984, Ger. Pat., Patent No. [3409065, 19843409065]

[9]

Dickore K, 1996, CHEM ABSTR, V104, P50897

[10]

Gally J J, 1982, CHEM ABSTR, V97

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