SYNTHESIS AND ANTIVIRAL ACTIVITY OF 3-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES

被引：86

作者：

ELHAKMAOUI, A

GUEIFFIER, A

MILHAVET, JC

BLACHE, Y

CHAPAT, JP

CHAVIGNON, O

TEULADE, JC

SNOECK, R

ANDREI, G

DECLERCQ, E

机构：

[1] LAB CHIM ORGAN PHARMACEUT,CNRS,URA 1111,F-34060 MONTPELLIER,FRANCE

[2] UNIV AUVERGNE,FAC PHARM,DEPT CHIM STRUCT & PHARMACOCHIM,F-63001 CLERMONT FERRAND,FRANCE

[3] KATHOLIEKE UNIV LEUVEN,REGA INST MED RES,B-3000 LOUVAIN,BELGIUM

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 16期

关键词：

D O I：

10.1016/S0960-894X(01)80538-2

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of 3-substituted imidazo[1,2-a]pyridines was synthesized as potential antiviral agents. Compound 10b and, to a lesser extent, 10c showed activity against both TK+ and TK- strains of varicella-zoster virus.

引用

页码：1937 / 1940

页数：4

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