ANALYSIS OF CROSS-OVER TRIALS WHEN WITHIN-SUBJECT ERRORS FOLLOW AN AR(1) PROCESS

被引：6
作者：
CHI, EM [1 ]
机构：
[1] BRISTOL MYERS SQUIBB,PRINCETON,NJ 08543
来源：
BIOMETRICAL JOURNAL | 1992年 / 34卷 / 03期
关键词：
GENERALIZED LEAST SQUARES ESTIMATE; RECOVERY OF INTERBLOCK INFORMATION; RESTRICTED LIKELIHOOD FUNCTION; WHITENING TRANSFORMATION;
D O I：
10.1002/bimj.4710340309
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
For cross-over trials with the assumption that the within-subject errors follow an AR(1) process, we propose a method, which is simple to compute, to obtain the generalized least squares estimates. The computation is easily implemented on any software that handles matrix manipulations.
引用
收藏
页码：359 / 365
页数：7
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