THE EFFECT OF CALCIUM AND MAGNESIUM-IONS ON URINARY UROKINASE AND SIALIDASE ACTIVITY

被引：14
|
作者：
VANASWEGEN, CH [1 ]
VANSCKALCKWYK, JCD [1 ]
DUTOIT, PJ [1 ]
VERSTER, L [1 ]
FRANZ, RC [1 ]
DUPLESSIS, DJ [1 ]
机构：
[1] UNIV PRETORIA,HF VERWOERD HOSP,DEPT SURG,PRETORIA 0001,SOUTH AFRICA
来源：
UROLOGICAL RESEARCH | 1992年 / 20卷 / 01期
关键词：
CALCIUM; KIDNEY STONES; MAGNESIUM; PLASMIN; SIALIDASE; UROKINASE;
D O I：
10.1007/BF00294333
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The effect of a promoter (calcium) and an inhibitor (magnesium) of urolithiasis was spectrophotometrically studied on urokinase (0.45 IU) and sialidase (5 mM). Although these mineral did not affect the sialidase activity, total inhibition of urokinase activity was observed with either 0.05 M calcium chloride or 0.1 M magnesium chloride. This observation might explain why calcium and magnesium respectively function as a promoter and an inhibitor of stone formation.
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页码：41 / 44
页数：4
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