DYSERYTHROPOIESIS, POLYMYOPATHY, AND CARDIAC DISEASE IN 3 RELATED ENGLISH SPRINGER-SPANIELS

被引:29
作者
HOLLAND, CT
CANFIELD, PJ
WATSON, ADJ
ALLAN, GS
机构
[1] UNIV SYDNEY,DEPT VET ANAT,SYDNEY,NSW 2006,AUSTRALIA
[2] UNIV SYDNEY,DEPT VET CLIN SCI,SYDNEY,NSW 2006,AUSTRALIA
[3] UNIV SYDNEY,DEPT VET PATHOL,SYDNEY,NSW 2006,AUSTRALIA
关键词
D O I
10.1111/j.1939-1676.1991.tb00942.x
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
A polysystemic disorder was observed in three related English Springer Spaniel dogs that demonstrated regurgitation from an early age, slowly progressive temporal muscle atrophy with partial trismus, and less pronounced generalized skeletal muscle atrophy. All dogs exhibited moderate dyserythropoietic anemia, polymyopathy with megaesophagus, and varying degrees of cardiomegaly. The prevalence, etiology, underlying pathomechanism, and possible mode of inheritance remain to be elucidated.
引用
收藏
页码:151 / 159
页数:9
相关论文
共 44 条
[21]  
Herbert V., Biology of disease: Megaloblastic anemias, Lab Invest, 52, pp. 3-19, (1985)
[22]  
Fresco R., Electron microscopy in the diagnosis of the bone marrow disorders of the erythroid series, Seminars Haematol, 18, pp. 279-292, (1981)
[23]  
Jain NC., The dog: Normal hematology with comments on response to disease, Schalm's Veterinary Hematology, pp. 103-125, (1986)
[24]  
Jain NC., Depression or hypoproliferative anaemias, Schalm's Veterinary Hematology, pp. 655-675, (1986)
[25]  
Giger U., Hereditary disorders of canine erythrocytes, Current Veterinary Therapy X, pp. 429-436, (1989)
[26]  
Appleyard ST, Dunn MJ, Dubowitz V., Et al., Monoclonal antibodies detect a spectrin‐like protein in normal and dystrophic human skeletal muscle, Proc Natl Acad Sci (USA), 81, pp. 776-780, (1984)
[27]  
Kakulas BA., Observations on the pathogenesis of Duchenne muscular dystrophy in the light of recent progress in molecular genetics, Aust Paediatr J, 24, pp. 4-8, (1988)
[28]  
Koenig M., Monaco AP, Kunkel LM., The complete sequence of dystrophin predicts a rod‐shaped cytoskeletal protein, Cell, 53, pp. 219-226, (1988)
[29]  
Stockman JA., Hematologic manifestations of systemic disease, Hematology of Infancy and Childhood, pp. 1659-1660, (1987)
[30]  
Kefton JG, Brain MC., Hemolytic anemias: Disorders of the red cell membrane, Hematology of Infancy and Childhood, (1987)