METALATION OF DIAZINES .2. 1ST METALATION OF PYRIDAZINE, METALATION OF 2,4-DICHLOROPYRIMIDINE

被引：34

作者：

TURCK, A

PLE, N

MOJOVIC, L

QUEGUINER, G

机构：

[1] Laboratoire de Chimie Organique Fine Et Hétérocyclique, Insa-Ircof, Mont Saint Aignan, 76131

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1990年 / 27卷 / 05期

关键词：

D O I：

10.1002/jhet.5570270536

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3,6‐Dichloropyridazine was ortho‐lithiated by lithium 2,2,6,6‐tetramethylpiperidide. The resulting lithio compound was reacted with carbonyl derivatives iodine and trimethylchlorosilane. An azaxanthone was synthesised. An unusual regioselectivity for the lithiation of 2,4‐dichloropyrimidine was studied. Copyright © 1990 Journal of Heterocyclic Chemistry

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页码：1377 / 1381

页数：5

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