2 CASES OF FATAL INTOXICATION DUE TO TRANYLCYPROMINE OVERDOSE

被引：8
|
作者：
BONIFACE, PJ
机构：
来源：
JOURNAL OF ANALYTICAL TOXICOLOGY | 1991年 / 15卷 / 01期
关键词：
D O I：
10.1093/jat/15.1.38
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Two cases of death following the ingestion of tranylcypromine are presented. High concentrations of tranylcypromine were determined in blood, urine, and liver by gas-liquid chromatography. Tranylcypromine was extracted from buffered blood with n-butyl chloride. The evaporated extract was derivatized with trifluoroacetic anhydride and analyzed by gas chromatography with nitrogen-phosphorus selective detection. The method was linear in blood over the range 0.5-20 mg/L with a limit of quantitation of about 0.2 mg/L.
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页码：38 / 40
页数：3
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