THE COPPER HALIDE-CATALYZED MONOSUBSTITUTION OF BROMINE IN ALPHA,OMEGA-DIBROMOALKANES BY GRIGNARD-REAGENTS - A REINVESTIGATION

被引：8

作者：

ANDRINGA, H ^{[1
]}

HANEKAMP, J ^{[1
]}

BRANDSMA, L ^{[1
]}

机构：

[1] STATE UNIV UTRECHT,DEBYE INST,DEPT SYNTHET ORGAN CHEM,PADUALAAN 8,3584 CH UTRECHT,NETHERLANDS

来源：

SYNTHETIC COMMUNICATIONS | 1990年 / 20卷 / 15期

关键词：

D O I：

10.1080/00397919008053179

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

,ω-Dibromoalkanes have been converted into mono-bromides R(CH2)nBr by reaction with the Grignard compounds RMgBr in THF in the presence of 5 mol % of copper(I)bromide. In contrast to what is suggested in the original literature, this method has a limited scope. © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：2349 / 2351

页数：3