ROLE OF THE LABORATORY IN INVESTIGATIONS OF CLOSTRIDIUM-DIFFICILE DIARRHEA

被引：43
作者：
BRAZIER, JS
机构：
[1] Anaerobe Reference Unit, Public Health Laboratory, University Hospital of Wales, Cardiff, Heath Park
来源：
CLINICAL INFECTIOUS DISEASES | 1993年 / 16卷
关键词：
D O I：
10.1093/clinids/16.Supplement_4.S228
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The laboratory diagnosis of acute diarrhea due to' Clostridium difficile can be based solely on the demonstration of either cytotoxin or enterotoxin in the stool. This and other noncultural methods, however, fail to provide isolates from which useful data can be obtained. Outbreaks can be recognized only by comparison of isolated strains. A dual approach of toxin detection and isolation is therefore recommended.
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页码：S228 / S233
页数：6
相关论文
共 47 条
[11]   ISOLATION OF CLOSTRIDIUM-DIFFICILE FROM STORED SPECIMENS AND COMPARATIVE SUSCEPTIBILITY OF VARIOUS TISSUE-CULTURE CELL-LINES TO CYTOTOXIN [J].
BOWMAN, RA ;
RILEY, TV .
FEMS MICROBIOLOGY LETTERS, 1986, 34 (01) :31-35
[12]   YELLOW FLUORESCENCE OF FUSOBACTERIA [J].
BRAZIER, JS .
LETTERS IN APPLIED MICROBIOLOGY, 1986, 2 (06) :125-126
[13]  
BRAZIER JS, 1990, CLINICAL AND MOLECULAR ASPECTS OF ANAEROBES, P293
[14]  
BRAZIER JS, 1989, STUDIES ULTRAVIOLET
[15]   SELECTIVE ENRICHMENT BROTH CULTURE FOR DETECTION OF CLOSTRIDIUM-DIFFICILE AND ASSOCIATED CYTO-TOXIN [J].
BUCHANAN, AG .
JOURNAL OF CLINICAL MICROBIOLOGY, 1984, 20 (01) :74-76
[16]   A SELECTIVE BROTH FOR CLOSTRIDIUM-DIFFICILE [J].
CARROLL, SM ;
BOWMAN, RA ;
RILEY, TV .
PATHOLOGY, 1983, 15 (02) :165-167
[17]   MULTICENTER EVALUATION OF A NEW ENZYME-IMMUNOASSAY FOR DETECTION OF CLOSTRIDIUM-DIFFICILE ENTEROTOXIN-A [J].
DEGIROLAMI, PC ;
HANFF, PA ;
EICHELBERGER, K ;
LONGHI, L ;
TERESA, H ;
PRATT, J ;
CHENG, A ;
LETOURNEAU, JM ;
THORNE, GM .
JOURNAL OF CLINICAL MICROBIOLOGY, 1992, 30 (05) :1085-1088
[18]   DEVELOPMENT OF A RAPID ENZYME-IMMUNOASSAY FOR CLOSTRIDIUM-DIFFICILE TOXIN-A AND ITS USE IN THE DIAGNOSIS OF C-DIFFICILE-ASSOCIATED DISEASE [J].
DIPERSIO, JR ;
VARGA, FJ ;
CONWELL, DL ;
KRAFT, JA ;
KOZAK, KJ ;
WILLIS, DH .
JOURNAL OF CLINICAL MICROBIOLOGY, 1991, 29 (12) :2724-2730
[19]  
ENSMINGER PW, 1982, CURRENT MICROBIOLOGY, V87, P59
[20]  
GEORGE WL, 1979, J CLIN MICROBIOL, V9, P214
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