HEMODYNAMIC-RESPONSES TO GRAM-POSITIVE VERSUS GRAM-NEGATIVE SEPSIS IN CRITICALLY ILL PATIENTS WITH AND WITHOUT CIRCULATORY SHOCK

被引：40

作者：

AHMED, AJ ^{[1
]}

KRUSE, JA ^{[1
]}

HAUPT, MT ^{[1
]}

CHANDRASEKAR, PH ^{[1
]}

CARLSON, RW ^{[1
]}

机构：

[1] WAYNE STATE UNIV,DEPT INTERNAL MED,DIV INFECT DIS,DETROIT,MI 48202

来源：

CRITICAL CARE MEDICINE | 1991年 / 19卷 / 12期

关键词：

BACTEREMIA; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HEMODYNAMICS; SEPTICEMIA; SHOCK; SEPTIC; CRITICAL CARE; BLOOD GAS ANALYSIS; CATHETERIZATION; CARDIAC OUTPUT;

D O I：

10.1097/00003246-199112000-00014

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Objective: To examine the hemodynamic patterns of critically ill patients with septicemia to evaluate their relationship to blood bacteriology. Design: Retrospective study. Setting: Medical ICUs of a tertiary care medical center. Patients: Total of 59 critically ill patients with bacteremia: 33 with Gram-positive and 26 with Gram-negative bacteremia. Measurements: Hemodynamic variables and mixed venous oxygen saturation (Svo2BAR) measurements associated with the highest cardiac index measured within 72 hrs of positive blood cultures. Main Results: No significant differences in cardiac index, mean arterial pressure, systemic vascular resistance, oxygen extraction ratio, or Svo2BAR were observed comparing the two groups. Conclusion: We were unable to demonstrate clinically important differences between the hemodynamic responses to Gram-positive vs. Gram-negative sepsis.

引用

页码：1520 / 1525

页数：6

共 37 条

[1] IMMEDIATE HEMODYNAMIC EFFECTS OF GRAM-NEGATIVE VS GRAM-POSITIVE BACTEREMIA IN MAN [J].

BLAIN, CM ;

ANDERSON, TO ;

PIETRAS, RJ ;

GUNNAR, RM .

ARCHIVES OF INTERNAL MEDICINE, 1970, 126 (02) :260-&

[2] SEPSIS SYNDROME - A VALID CLINICAL ENTITY [J].

BONE, RC ;

FISHER, CJ ;

CLEMMER, TP ;

SLOTMAN, GJ ;

METZ, CA ;

BALK, RA .

CRITICAL CARE MEDICINE, 1989, 17 (05) :389-393

[3]

Buetler B., 1985, SCIENCE, V229, P869

[4]

DANNER RL, 1989, NEW HORIZONS MULTIPL, P151

[5]

DINARELLO CA, 1984, NEW ENGL J MED, V311, P1413

[6] IMPORTANCE OF BETA, TYPE-II ERROR AND SAMPLE-SIZE IN DESIGN AND INTERPRETATION OF RANDOMIZED CONTROL TRIAL - SURVEY OF 71 NEGATIVE TRIALS [J].

FREIMAN, JA ;

CHALMERS, TC ;

SMITH, H ;

KUEBLER, RR .

NEW ENGLAND JOURNAL OF MEDICINE, 1978, 299 (13) :690-694

[7] HEMODYNAMIC MEASUREMENTS IN BACTEREMIA AND SEPTIC SHOCK IN MAN [J].

GUNNAR, RM ;

LOEB, HS ;

WINSLOW, EJ ;

BLAIN, C ;

ROBINSON, J .

JOURNAL OF INFECTIOUS DISEASES, 1973, 128 (JUL) :S295-S298

[8] SPECTRUM OF CARDIOVASCULAR FUNCTION DURING GRAM-NEGATIVE SEPSIS [J].

HESS, ML ;

HASTILLO, A ;

GREENFIELD, LJ .

PROGRESS IN CARDIOVASCULAR DISEASES, 1981, 23 (04) :279-298

[9] TOXIC SHOCK SYNDROME TOXIN-1 AS AN INDUCER OF HUMAN-TUMOR NECROSIS FACTORS AND GAMMA-INTERFERON [J].

JUPIN, C ;

ANDERSON, S ;

DAMAIS, C ;

ALOUF, JE ;

PARANT, M .

JOURNAL OF EXPERIMENTAL MEDICINE, 1988, 167 (03) :752-761

[10] AN EVALUATION OF OUTCOME FROM INTENSIVE-CARE IN MAJOR MEDICAL-CENTERS [J].

KNAUS, WA ;

DRAPER, EA ;

WAGNER, DP ;

ZIMMERMAN, JE .

ANNALS OF INTERNAL MEDICINE, 1986, 104 (03) :410-418

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