GLIAL POPULATIONS IN THE JUVENILE AND ADULT MONGOLIAN GERBIL - RELATIONSHIP TO SPONGIFORM DEGENERATION OF THE VENTRAL COCHLEAR NUCLEUS

被引：16
|
作者：
FADDIS, BT
MCGINN, MD
机构：
[1] Department of Otolaryngology, Head and Neck Surgery, University of California, Davis
来源：
EXPERIMENTAL NEUROLOGY | 1993年 / 120卷 / 02期
关键词：
D O I：
10.1006/exnr.1993.1051
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The gerbil cochlear nucleus is subject to a spongiform degeneration, the progression of which is dependent on auditory functional activity. The most affected region is the ventrolateral aspect of the caudal posterior ventral cochlear nucleus (PVCN). Lesion density and glial changes were quantified in this region for two age groups. Spongiform lesions increased significantly in area density from 4% in 60-day-old gerbils to 14% in 6-month-old gerbils. In spite of this significant increase in tissue damage, no gliosis was found. A significant age-related decrease in oligodendrocyte density was found in the PVCN. © 1994 Academic Press. All rights reserved.
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页码：160 / 169
页数：10
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