SOLUBILITY ENHANCEMENT OF TRIFLUMIZOLE BY HOST-GUEST INTERACTION WITH BETA-CYCLODEXTRIN

被引：8

作者：

VIERNSTEIN, H ^{[1
]}

REITER, S ^{[1
]}

WOLSCHANN, P ^{[1
]}

机构：

[1] UNIV VIENNA,INST THEORET CHEM & STRAHLENCHEM,A-1090 VIENNA,AUSTRIA

来源：

MONATSHEFTE FUR CHEMIE | 1994年 / 125卷 / 6-7期

关键词：

BETA-CYCLODEXTRIN; HOST GUEST COMPLEX; INCLUSION COMPLEX; MOLECULAR MODELING; SOLUBILITY ENHANCEMENT; TRIFLUMIZOLE;

D O I：

10.1007/BF01277627

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The solubility enhancement of triflumizole, a systemic fungicide, by beta-cyclodextrin inclusion complexation was investigated by electron absorption spectroscopy. The respective association constant determined by different methods was estimated to 470 +/- 20 M-1 in aqueous solution. A model for the host-guest complexation was deduced by molecular calculations.

引用

页码：681 / 689

页数：9

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