REACTIONS OF 1.0 NANOMETRE DIAMETER PU-238 DIOXIDE PARTICLES WITH RAT LUNG FLUID

被引：16
作者：
COOPER, JR
STRADLING, GN
SMITH, H
BREADMORE, SE
机构：
[1] National Radiological Protection Board, Harwell, Didcot, Oxon
来源：
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY | 1979年 / 36卷 / 05期
关键词：
D O I：
10.1080/09553007914551251
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The reactions of 1·0 nm particles of plutonium-238 dioxide with rat lung fluid have been studied both in vivo and in vitro. In both cases two products have been identified, (i) plutonium-labelled pulmonary surfactant and (ii) a heterogeneous plutonium-labelled material isolated by column chromatography. The formation of plutonium-labelled pulmonary surfactant results in the rapid translocation of plutonium from lungs to blood and in a high urinary excretion relative to administered plutonium citrate. © 1979 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码：453 / 466
页数：14
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