7-{[2-(4-Hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicAcid

被引：0
|
作者：
Fareed, Ghulam [1 ,2 ]
Kalhoro, Mahboob A. [1 ]
Versiani, Muhammad A. [2 ]
Afza, Nighat [1 ]
Fareed, Nazia [2 ]
机构：
[1] PCSIR Lab, Pharmaceut Res Ctr, Complex Kara,Shahrah E Dr Salim Uz Zaman Siddiqui, Karachi 75280, Sindh, Pakistan
[2] Fed Urdu Univ Arts Sci & Technol, Dept Chem, Karachi 75300, Sindh, Pakistan
来源：
MOLBANK | 2012年 / 02期
关键词：
ceftriaxone; 4-hydroxybenzaldehyde;
D O I：
10.3390/M756
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Novel 7-{[2-(4-hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl) sulfanyl]methyl}-8-oxo-5-thia-1azabicyclo [4.2.0]oct-2-ene-2-carboxylic acid was prepared by condensation of ceftriaxone disodium (1) with 4-hydroxybenzaldehyde (2) in ethanol under reflux conditions for 3-4 h. The structure of synthesized compound was elucidated using LCMS, H-1-NMR, and CHN techniques.
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页数：3
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