PHOSPHONOMYCIN, A NEW ANTIBIOTIC PRODUCED BY STRAINS OF STREPTOMYCES

被引：543

作者：

HENDLIN, D

STAPLEY, EO

JACKSON, M

WALLICK, H

MILLER, AK

WOLF, FJ

MILLER, TW

CHAIET, L

KAHAN, FM

FOLTZ, EL

WOODRUFF, HB

机构：

[1] Merck Institute for Therapeutic, Research-Merck Sharp and Dohme Research Laboratories, Rahway, NJ

[2] Compañía Española de la Penicilina y Antibioticos, Madrid

来源：

SCIENCE | 1969年 / 166卷 / 3901期

关键词：

D O I：

10.1126/science.166.3901.122

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Phosphonomycin is a newly discovered antibiotic produced by streptomycetes. It is effective, when administered by the oral route, to mice infected with Gram-positive or Gram-negative microorganisms. The antibiotic is bactericidal and inhibits cell-wall synthesis.

引用

页码：122 / &

共 10 条

[1]

CHAIET L, IN PREPARATION

[2] PHOSPHONOMYCIN - STRUCTURE AND SYNTHESIS [J].