Markers of Oxidative Stress in Patients with Coronary Heart Disease

被引:1
作者
Kotova, Julia A. [1 ]
Zuikova, Anna A. [1 ]
Pashkov, Alexander N. [1 ]
Strahova, Natalia V. [1 ]
Krasnorutskaya, Olga N. [1 ]
机构
[1] Voronezh State Med Univ, Voronezh, Russia
关键词
oxidative modification of proteins; superoxide dismutase; oxidative stress; coronary heart disease;
D O I
10.21103/Article8(2)_OA1
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The aim of this research was to study the blood levels of protein oxidation products and superoxide dismutase (SOD) activity and their relationship with lipid profile parameters in patients with coronary heart disease (CHD). In CHD patients, against a background of low SOD activity, the protein carbonyl content (PCC) level was significantly higher than in the control group. In addition, significant correlations were found between the indices of PCC. SOD activity, and lipid profile parameters. The determination of PCC parameters can serve as a good indicator of the severity of atherosclerosis.
引用
收藏
页码:115 / 117
页数:3
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