Scaffold-associated regions: cis-acting determinants of chromatin structural loops and functional domains

被引：319
作者：
Laemmli, Ulrich K. [1 ]
Kaes, Emmanuel [1 ]
Poljak, Leonora [1 ]
Adachi, Yasuhisa [1 ]
机构：
[1] Univ Geneva, Dept Biochem & Mol Biol, 30 Quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 1992年 / 2卷 / 02期
关键词：
D O I：
10.1016/S0959-437X(05)80285-0
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
It has been proposed that scaffold-associated regions are DNA elements that form the bases of chromatin loops in eukaryotic cells. Recent evidence supports a role for these elements as cis-acting 'handlers' of both structural and functional chromatin domains.u
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页码：275 / 285
页数：11
相关论文
共 69 条
[1]   PHOSPHORYLATION OF DNA TOPOISOMERASE-II BY CASEIN KINASE-II - MODULATION OF EUKARYOTIC TOPOISOMERASE-II ACTIVITY INVITRO [J].
ACKERMAN, P ;
GLOVER, CVC ;
OSHEROFF, N .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (10) :3164-3168
[2]   PREFERENTIAL, COOPERATIVE BINDING OF DNA TOPOISOMERASE-II TO SCAFFOLD-ASSOCIATED REGIONS [J].
ADACHI, Y ;
KAS, E ;
LAEMMLI, UK .
EMBO JOURNAL, 1989, 8 (13) :3997-4006
[3]   CHROMOSOME ASSEMBLY INVITRO - TOPOISOMERASE-II IS REQUIRED FOR CONDENSATION [J].
ADACHI, Y ;
LUKE, M ;
LAEMMLI, UK .
CELL, 1991, 64 (01) :137-148
[4]   CPG ISLANDS AS GENE MARKERS IN THE VERTEBRATE NUCLEUS [J].
BIRD, AP .
TRENDS IN GENETICS, 1987, 3 (12) :342-347
[5]  
BLASQUEZ VC, 1989, J BIOL CHEM, V264, P21183
[6]   BIOLOGICAL SIGNIFICANCE OF UNWINDING CAPABILITY OF NUCLEAR MATRIX ASSOCIATING DNAS [J].
BODE, J ;
KOHWI, Y ;
DICKINSON, L ;
JOH, T ;
KLEHR, D ;
MIELKE, C ;
KOHWISHIGEMATSU, T .
SCIENCE, 1992, 255 (5041) :195-197
[7]   TISSUE SPECIFIC AND POSITION INDEPENDENT EXPRESSION OF THE COMPLETE GENE DOMAIN FOR CHICKEN LYSOZYME IN TRANSGENIC MICE [J].
BONIFER, C ;
VIDAL, M ;
GROSVELD, F ;
SIPPEL, AE .
EMBO JOURNAL, 1990, 9 (09) :2843-2848
[8]   DNA METHYLATION INHIBITS TRANSCRIPTION INDIRECTLY VIA A METHYL-CPG BINDING-PROTEIN [J].
BOYES, J ;
BIRD, A .
CELL, 1991, 64 (06) :1123-1134
[9]   PROTEIN MOTIFS THAT RECOGNIZE STRUCTURAL FEATURES OF DNA [J].
CHURCHILL, MEA ;
TRAVERS, AA .
TRENDS IN BIOCHEMICAL SCIENCES, 1991, 16 (03) :92-97
[10]   CHROMOSOMAL LOOP ANCHORAGE OF THE KAPPA IMMUNOGLOBULIN GENE OCCURS NEXT TO THE ENHANCER IN A REGION CONTAINING TOPOISOMERASE-II SITES [J].
COCKERILL, PN ;
GARRARD, WT .
CELL, 1986, 44 (02) :273-282
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