EFFECT OF NOCARDIA-RUBRA CELL-WALL SKELETON ON THE INDUCTION OF LUNG-CANCER IN ACI-N RATS

被引：0

作者：

NAMBA, M ^{[1
]}

YOSHIMOTO, T ^{[1
]}

OGURA, T ^{[1
]}

HIRAO, F ^{[1
]}

AZUMA, I ^{[1
]}

YAMAMURA, Y ^{[1
]}

机构：

[1] OSAKA UNIV, SCH MED, DEPT INTERNAL MED 3, FUKUSHIMA KU, OSAKA 553, JAPAN

来源：

GANN | 1979年 / 70卷 / 01期

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In ACI/N rats administration of oil-attached N. rubra cell-wall skeleton (CWS) was evaluated for its effect on lung cancer induction. Lung cancers were induced by 15 weekly intratracheal instillations of 3 mg benzo[a] pyrene with 3 mg ferric oxide. After the 10th instillation of the carcinogen, rats received 7 s.c. injections of 100 .mu.g of N. rubra-CSW at 2 wk intervals. In the observation period of 56 wk, the cumulative incidence of lung cancer was 71.4% in the control group and 48.0% in the N. rubra-CWS treated group. The latent period of tumor induction was prolonged in the group treated with N. rubra-CWS.

引用

页码：55 / +

页数：1

共 28 条

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