SYNTHESIS AND PROPERTIES OF OLIGONUCLEOTIDE(2-AMINOETHYL)PHOSPHONATES

被引：2
|
作者：
COOK, AF
FATHI, R
HUANG, Q
COPPOLA, G
DELANEY, W
SYI, JL
机构：
[1] PharmaGenics, Inc., 4 Pearl Court, Allendale New Jersey
来源：
NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 3-5期
关键词：
D O I：
10.1080/15257779508012521
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Oligonucleotides with novel, cationic backbone substituents have been prepared. Dinucleotide aminoethylphosphonates have been synthesized and the isomers were separated and used to prepare oligonucleotides with alternating positive and negative charges. The properties of these oligonucleotides have been examined.
引用
收藏
页码：1005 / 1008
页数：4
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