ELASCLEPIAL AND OTHER TETRACYCLIC DITERPENOIDS FROM ELAEOSELINUM-ASCLEPIUM

被引：15

作者：

GRANDE, M ^{[1
]}

MANCHENO, B ^{[1
]}

SANCHEZ, MJ ^{[1
]}

机构：

[1] UNIV ALICANTE,DEPT CIENCIAS AMBIENTALES & RECURSOS NAT,DIV QUIM ORGAN,E-03080 ALICANTE,SPAIN

来源：

PHYTOCHEMISTRY | 1991年 / 30卷 / 06期

关键词：

ELAEOSELINUM-ASCLEPIUM; UMBELLIFERAE; ROOTS; BEYERANE; KAURANE AND ATISANE DITERPENE ACIDS; ELASCLEPIC ACID; DITERPENE ALDEHYDES; ELASCLEPIAL;

D O I：

10.1016/0031-9422(91)85051-Z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The neutral components of the benzene extract from Elaeoselinum asclepium roots were identified as elasclepiol, erythroxylol A and four new beyerane diterpene aldehydes, ent-14-beta-tigloyloxybeyer-15-en-19-al (elasclepial) and its 14-beta-angeloyloxy- isomer, and ent-3-beta-hydroxy-14-beta-tigloyloxybeyer-15-en-19-al (3-beta-hydroxyelasclepial) and its acetate. These axial aldehydes were oxidized by atmospheric oxygen to the respective carboxylic acids and decarbonylated to give hydroperoxides. Four new tetracyclic diterpene acids have been isolated from the acid fraction of the benzene extract and identified as ent-14-beta-angeloyloxybeyer-15-en-19-oic acid, ent-beyer-15-en-19-oic acid, entatis-16-en-19-oic acid and ent-18-angeloyloxykaur-16-en-19-oic acid. The structures of the compounds described were established by spectroscopic methods and chemical correlations.

引用

页码：1977 / 1982

页数：6

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