IMPROVED DELIVERY THROUGH BIOLOGICAL-MEMBRANES .4. PRODRUGS OF L-DOPA

被引：66
作者：
BODOR, N
SLOAN, KB
HIGUCHI, T
SASAHARA, K
机构：
[1] INTER RES CORP,LAWRENCE,KS 66044
[2] SANKYO CO LTD,TOKYO 140,JAPAN
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1977年 / 20卷 / 11期
关键词：
D O I：
10.1021/jm00221a014
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：1435 / 1445
页数：11
相关论文
共 34 条
[1]   ABSORPTION AND METABOLISM OF LEVODOPA [J].
ABRAMS, WB ;
COUTINHO, CB ;
LEON, AS ;
SPIEGEL, HE .
JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1971, 218 (13) :1912-&
[2]   DRUGS AFFECTING MOVEMENT DISORDERS [J].
BARBEAU, A .
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1974, 14 :91-113
[3]  
BARBEAU A, 1975, LANCET, V1, P756
[4]  
BIANCHINE J R, 1976, Clinical Pharmacokinetics, V1, P313, DOI 10.2165/00003088-197601050-00001
[5]  
BODOR N, 1976, Patent No. 3998799
[6]  
Bodor N. S., 1975, US Patent, Patent No. [3,891,696, 3891696]
[7]   HERSTELLUNG VON ALPHA-AMINOSAUREESTERN DURCH ALKOHOLYSE DER METHYLESTER [J].
BRENNER, M ;
HUBER, W .
HELVETICA CHIMICA ACTA, 1953, 36 (05) :1109-1115
[8]   CONJUGATION OF L-DOPA AND ITS METABOLITES AFTER ORAL AND INTRAVENOUS ADMINISTRATION TO PARKINSONIAN PATIENTS [J].
BRONAUGH, RL ;
MCMURTRY, RJ ;
HOEHN, MM ;
RUTLEDGE, CO .
BIOCHEMICAL PHARMACOLOGY, 1975, 24 (13-1) :1317-1320
[9]  
Brossi A, 1974, Adv Neurol, V5, P291
[10]   SYNTHESIS AND ANTIRESERPINE ACTIVITY OF PEPTIDES OF L-DOPA [J].
FELIX, AM ;
WINTER, DP ;
WANG, SS ;
KULESHA, ID ;
POOL, WR ;
HANE, DL ;
SHEPPARD, H .
JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (04) :422-426
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