DIASTEREOSELECTIVE AND ENANTIOSELECTIVE SYNTHESIS OF (-)-OUDEMANSIN-A VIA [2,3]-WITTIG REARRANGEMENT OF CROTYLOXYACETALDEHYDE-SAEP-HYDRAZONE

被引：0

作者：

ENDERS, D

BARTSCH, M

BACKHAUS, D

机构：

来源：

SYNLETT | 1995年 / 08期

关键词：

OUDEMANSIN A; 2,3]-WITTIG REARRANGEMENT; MAGNESIUM MONOPEROXYPHTHALATE; CHIRAL HYDRAZONE; ASYMMETRIC SYNTHESIS;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of (-)-oudemansin A (1) was accomplished in a ten - step sequence with good overall yield (20%) and excellent diastereo- and enantiomeric excesses (de, ee greater than or equal to 98%). Key step of the synthesis is the asymmetric [2,3]-Wittig rearrangement of crotyloxyacetaldehyde-SAEP-hydrazone [(S)-6].

引用

页码：869 / 870

页数：2

共 25 条

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