DIASTEREOSELECTIVE AND ENANTIOSELECTIVE SYNTHESIS OF (-)-OUDEMANSIN-A VIA [2,3]-WITTIG REARRANGEMENT OF CROTYLOXYACETALDEHYDE-SAEP-HYDRAZONE

被引：0
|
作者：
ENDERS, D
BARTSCH, M
BACKHAUS, D
机构：
来源：
SYNLETT | 1995年 / 08期
关键词：
OUDEMANSIN A; 2,3]-WITTIG REARRANGEMENT; MAGNESIUM MONOPEROXYPHTHALATE; CHIRAL HYDRAZONE; ASYMMETRIC SYNTHESIS;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The total synthesis of (-)-oudemansin A (1) was accomplished in a ten - step sequence with good overall yield (20%) and excellent diastereo- and enantiomeric excesses (de, ee greater than or equal to 98%). Key step of the synthesis is the asymmetric [2,3]-Wittig rearrangement of crotyloxyacetaldehyde-SAEP-hydrazone [(S)-6].
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页码：869 / 870
页数：2
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