CONTINUOUS-INFUSION OF VANCOMYCIN IN POSTSURGERY STAPHYLOCOCCAL MENINGITIS OF ADULTS

被引:0
|
作者
BRINQUIN, L [1 ]
ROUSSEAU, JM [1 ]
BOULESTEIX, G [1 ]
DIRAISON, Y [1 ]
BONSIGNOUR, JP [1 ]
机构
[1] HIA VAL DE GRACE,SERV REANIMAT,74 BLVD PORT ROYAL,F-75230 PARIS 05,FRANCE
来源
PRESSE MEDICALE | 1993年 / 22卷 / 36期
关键词
VANCOMYCIN; MENINGITIS; STAPHYLOCOCCUS;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Eight adult patients with post-surgery meningitis caused by methicillin-resistant staphylococci were treated with continuous intravenous infusion of vancomycin in mean doses of 50 mg/kg/day. This treatment, which lasted 3 to 6 weeks, was well tolerated by the kidneys and resulted in cure in all cases; its effect on the ear was not evaluated. Stable concentrations of 4 to 7 mg/l in cerebrospinal fluid were obtained after the 48th hour of treatment.
引用
收藏
页码:1815 / 1817
页数:3
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