CONJUNCTIVAL FLORA IN EXTENDED WEAR OF RIGID GAS PERMEABLE CONTACT-LENSES

被引：18
作者：
FLEISZIG, SMJ
EFRON, N
机构：
[1] Corneal Biophysics Laboratory, Department of Optometry, University of Melbourn, Parkville, VIC
来源：
OPTOMETRY AND VISION SCIENCE | 1992年 / 69卷 / 05期
关键词：
CONTACT LENSES; CONJUNCTIVAL FLORA; INFECTIOUS KERATITIS; EXTENDED WEAR;
D O I：
10.1097/00006324-199205000-00004
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
A longitudinal study was performed to examine the effect of rigid gas permeable (RGP) contact lenses (Boston Equalens II and Quantum II) on the conjunctival flora of 45 young healthy subjects. Microbial flora were determined before delivery of lenses. Subjects wore lenses on an extended wear basis, removing them every 7 days for cleaning and disinfection. Cultures were repeated after 2 months of lens wear and the microbial flora were found to be significantly altered compared to the prelens wear results (0.05 > p > 0.02). Changes to conjunctival flora included an increase in the number of eyes from which potentially pathogenic microorganisms were isolated, an increase in the number of eyes that were culture-negative, and a decrease in the number of eyes harboring only normal conjunctival flora. The increase in potentially pathogenic flora was not specific for Gram-negative bacteria, which are most often associated with infectious keratitis during contact lens wear.
引用
收藏
页码：354 / 357
页数：4
相关论文
共 17 条
  • [1] Alfonso E., Mandelbaum S., Fox M.J., Forster R.K., Ulcerative keratitis associated with contact lens wear, Am J Ophthalmol, 101, pp. 429-433, (1986)
  • [2] Poggio E.C., Glynn R.J., Schein O.D., Seddon J.M., Shannon M.J., Scardino V.A., Kenyon K.R., The incidence of ulcerative keratitis among users of daily-wear and extended wear soft contact lenses, N Engl J Med, 321, pp. 779-783, (1989)
  • [3] Schein O.D., Glynn R.J., Poggio E.C., Seddon J.M., Kenyon K.R., The relative risk of ulcerative keratitis among users of daily wear and extended-wear soft contact lenses, N Engl J Med, 321, pp. 773-778, (1989)
  • [4] Brennan N.A., Efron N., Weissman B.A., Harris M.G., Clinical application of the oxygen transmissibility of powered contact lenses, Contact Lens Assoc Ophthalmol J, 17, pp. 169-172, (1991)
  • [5] Ehrlich M., Weissman B.A., Mondino B.J., Pseudomonas, Cornea, 8, pp. 225-226, (1989)
  • [6] Smolin G., Okumoto M., Nozik R.A., The microbial flora in extended-wear soft contact lens-wearers, Am J Ophthalmol, 88, pp. 543-547, (1979)
  • [7] Winkler C.H., Dixon J.M., Bacteriology of the eye, Arch Ophthalmol, 72, pp. 817-819, (1964)
  • [8] Callender M.G., Tse L., Charles A.M., Lutzi D., Bacterial flora of the eye and contact lens cases during hydrogel lens wear, Am J Optom Physiol Opt, 63, pp. 177-180, (1986)
  • [9] Lennette E.H., Balows A., Hausler W.J., Shadomy H.J., Manual of Clinical Microbiology. Washington, D.C.: American Society of Microbiology, (1985)
  • [10] McNatt J., Allen S.D., Wilson L.A., Dowell V.R., Anaerobic flora of the normal human conjunctival sac, Arch Ophthalmol, 96, pp. 1448-1450, (1978)
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