SUBSTANCE-P-LIKE IMMUNOREACTIVITY AT THE FROG NEUROMUSCULAR-JUNCTION

被引：26

作者：

MATTEOLI, M

HAIMANN, C

DECAMILLI, P

机构：

[1] CNR,CTR CYTOPHARMACOL,DEPT MED PHARMACOL,I-20133 MILAN,ITALY

[2] CNR,CTR STUDY PERIPHERAL NEUROPATHIES & NEUROMUSC DIS,I-20133 MILAN,ITALY

[3] YALE UNIV,SCH MED,DEPT CELL BIOL,NEW HAVEN,CT 06510

来源：

NEUROSCIENCE | 1990年 / 37卷 / 01期

关键词：

D O I：

10.1016/0306-4522(90)90213-N

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

It has been recently shown that frog motoneurons and their nerve terminals contain calcitonin gene-related peptide-like immunoreactivity in large dense-core vesicles (Matteoli et al., Proc. natn. Acad. Sci. U.S.A. 85, 7366-7370, 1988). We report here by an immunofluorescence approach that the same neurons and nerve terminals also contain substance P-like immunoreactivity. The demonstration of substance P-like immunoreactivity in the frog motor nerve endings supports previous data suggesting a physiological role for this peptide in the modulation of cholinergic transmission. © 1990.

引用

页码：271 / 275

页数：5

共 34 条

[1] SUBSTANCE-P MODULATES THE SENSITIVITY OF THE NICOTINIC RECEPTOR IN AMPHIBIAN CHOLINERGIC TRANSMISSION
AKASU, T
KOJIMA, M
KOKETSU, K
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1983, 80 (01) : 123 - 131
[2] ALTERNATIVE RNA PROCESSING IN CALCITONIN GENE-EXPRESSION GENERATES MESSENGER-RNAS ENCODING DIFFERENT POLYPEPTIDE PRODUCTS
AMARA, SG
JONAS, V
ROSENFELD, MG
ONG, ES
EVANS, RM
[J]. NATURE, 1982, 298 (5871) : 240 - 244
[3] SUBSTANCE-P IN THE ADRENAL-GLAND - ORIGIN AND SPECIES DISTRIBUTION
BUCSICS, A
SARIA, A
LEMBECK, F
[J]. NEUROPEPTIDES, 1981, 1 (05) : 329 - 341
[4] CLAPHAM DE, 1984, J PHYSIOL-LONDON, V347, P255, DOI 10.1113/jphysiol.1984.sp015065
[5] VESICULAR LOCALIZATION OF IMMUNOREACTIVE [MET5]ENKEPHALIN IN THE GLOBUS PALLIDUS
COULTER, HD
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (18) : 7028 - 7032
[6] SYNAPSIN-I (PROTEIN-I), A NERVE TERMINAL-SPECIFIC PHOSPHOPROTEIN .1. ITS GENERAL DISTRIBUTION IN SYNAPSES OF THE CENTRAL AND PERIPHERAL NERVOUS-SYSTEM DEMONSTRATED BY IMMUNOFLUORESCENCE IN FROZEN AND PLASTIC SECTIONS
DECAMILLI, P
CAMERON, R
GREENGARD, P
[J]. JOURNAL OF CELL BIOLOGY, 1983, 96 (05) : 1337 - 1354
[7] DECAMILLI P, 1988, J NEUROSCI, V8, P1625
[8] ACTIVATORS OF PROTEIN-KINASE-C ENHANCE ACETYLCHOLINE-RECEPTOR DESENSITIZATION IN SYMPATHETIC-GANGLION NEURONS
DOWNING, JEG
ROLE, LW
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (21) : 7739 - 7743
[9] SUBSTANCE-P DEPOLARIZES NERVE-TERMINALS IN AN AUTONOMIC GANGLION
DRYER, SE
CHIAPPINELLI, VA
[J]. BRAIN RESEARCH, 1985, 336 (01) : 190 - 194
[10] DUN NJ, 1985, NEUROTRANSMITTER ACT, P385

← 1 2 3 4 →