EFFECT OF LOW-DENSITY LIPOPROTEINS ON SECRETION OF PLASMINOGEN-ACTIVATOR INHIBITOR-1 (PAI-1) BY HUMAN ENDOTHELIAL-CELLS AND HEPATOMA-CELLS

被引：23

作者：

LATRON, Y

ALESSI, MC

ANFOSSO, F

NALBONNE, G

LAFONT, H

PORTUGAL, H

JUHANVAGUE, I

机构：

[1] INSERM, LIPID TRANSPORT LAB, U130, F-13258 MARSEILLE 09, FRANCE

[2] HOSP SAINTE, CENT LAB ANAL, MARSEILLE, FRANCE

来源：

FIBRINOLYSIS | 1990年 / 4卷

关键词：

Atherosclerosis; Endothelial cells; Hepatocyte; Low density lipoproteins; Plasminogen activator inhibitor 1;

D O I：

10.1016/0268-9499(90)90368-T

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The secretion of PAI-1 was measured in the conditioned medium of confluent cultures of Hep G2 cells and human umbilical vein endothelial cells (HUVEC) after low density lipoproteins (LDL) stimulation. LDL induced a dose-dependent increase in PAI-1 Ag synthesis by Hep G2 cells. They did not modify the basal level of PAI-1 secretion by HUVEC. © 1990.

引用

页码：82 / 83

页数：2

共 15 条

[1]

ALESSI MC, 1988, THROMB HAEMOSTASIS, V60, P491

[2] CATABOLISM OF HUMAN LOW-DENSITY LIPOPROTEINS BY HUMAN HEPATOMA-CELL LINE HEPG2 [J].