FAST ATOM BOMBARDMENT - A NEW MASS-SPECTROMETRIC METHOD FOR PEPTIDE SEQUENCE-ANALYSIS

被引:216
作者
MORRIS, HR [1 ]
PANICO, M [1 ]
BARBER, M [1 ]
BORDOLI, RS [1 ]
SEDGWICK, RD [1 ]
TYLER, A [1 ]
机构
[1] UNIV MANCHESTER, INST SCI & TECHNOL, DEPT CHEM, MANCHESTER M60 1QD, LANCASHIRE, ENGLAND
关键词
D O I
10.1016/0006-291X(81)91304-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A selection of peptides was studied using a new mass spectrometric ionization technique, fast atom bombardment. The fragmentation pathways observed and the utility in sequence analysis are discussed. A simple acetylation experiment is shown to aid rapid sequence assignment.
引用
收藏
页码:623 / 631
页数:9
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