Datasets describing the growth and molecular features of hepatocellular carcinoma patient-derived xenograft cells grown in a three-dimensional macroporous hydrogel

被引：3

作者：

Fong, Eliza Li Shan ^{[1
]}

Toh, Tan Boon ^{[2
]}

Lin, Quy Xiao Xuan ^{[2
]}

Liu, Zheng ^{[3
]}

Hooi, Lissa ^{[2
]}

Rashid, Masturah Bte Mohd Abdul ^{[2
]}

Benoukraf, Touati ^{[2
]}

Chow, Edward Kai-Hua ^{[2
,10
]}

The Hung Huynh ^{[4
]}

Yu, Hanry ^{[3
,5
,6
,7
,8
,9
]}

机构：

[1] Natl Univ Singapore, Dept Biomed Engn, Singapore, Singapore

[2] Natl Univ Singapore, Canc Sci Inst Singapore, Singapore, Singapore

[3] ASTAR, Inst Bioengn & Nanotechnol, Singapore, Singapore

[4] Natl Canc Ctr Singapore, Singapore, Singapore

[5] Natl Univ Singapore, Dept Physiol, Yong Loo Lin Sch Med, Singapore, Singapore

[6] Natl Univ Singapore, Mechanobiol Inst, Singapore, Singapore

[7] Singapore MIT Alliance Res & Technol, BioSyM, Singapore, Singapore

[8] Southern Med Univ, Dept Gastroenterol, Nanfang Hosp, Guangzhou, Guangdong, Peoples R China

[9] Natl Univ Singapore, NUS Grad Sch Integrat Sci & Engn, Singapore, Singapore

[10] Natl Univ Singapore, Dept Pharmacol, Yong Loo Lin Sch Med, Singapore, Singapore

来源：

DATA IN BRIEF | 2018年 / 18卷

基金：

英国医学研究理事会; 新加坡国家研究基金会;

关键词：

D O I：

10.1016/j.dib.2018.03.045

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This data article presents datasets associated with the research article entitled "Generation of matched patient-derived xenograft in vitro-in vivo models using 3D macroporous hydrogels for the study of liver cancer" (Fong et al., 2018) [1]. A three-dimensional macroporous sponge system was used to generate in vitro counterparts to various hepatocellular carcinoma patient-derived xenograft (HCC-PDX) lines. This article describes the viability, proliferative capacity and molecular features (genomic and transcriptomic profiles) of the cultured HCC-PDX cells. The sequencing datasets are made publicly available to enable critical or further analyzes. (C) 2018 The Authors. Published by Elsevier lnc.

引用

页码：594 / 606

页数：13

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