EXPRESSION OF GAMMA-DELTA LYMPHOCYTES-T DERIVED FROM HUMAN INTESTINAL BIOPSIES

被引：4
|
作者：
VOLK, BA
NIESSNER, M
AMANN, B
FAUSER, AA
GEROK, W
机构：
[1] Innere Medizin II, Abteilung Gastroenterologie und Hepatologie der Universität Freiburg, Medizinische Universitätsklinik Freiburg, Freiburg
来源：
IMMUNOLOGIC RESEARCH | 1991年 / 10卷 / 3-4期
关键词：
D O I：
10.1007/BF02919713
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Although most T cells express the alpha/beta-TCR, the gamma/delta-TCR is expressed only on a small percentage of peripheral lymphocytes and CD3+ intestinal T cells. The most striking feature is a wide variation in the proportion of gamma/delta+ T cells in freshly isolated peripheral blood cells from normal individuals and patients with IBD. The augmentation of the gamma/delta+ T cell subpopulation derived from human intestinal biopsies after repeated stimulation with MT, even in the absence of filler cells, suggests that gamma/delta+ cells from human gut mucosa may play a role in generating a primary immune response to MT.
引用
收藏
页码：310 / 312
页数：3
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