SERUM SOLUBLE INTERLEUKIN-2 RECEPTOR IN PATIENTS WITH GLOMERULONEPHRITIS

被引：18
作者：
YORIOKA, N
HIRABAYASHI, A
KANAHARA, K
TAKEMASA, A
ODA, H
JOARDER, ZH
YAMAKIDO, M
机构：
来源：
AMERICAN JOURNAL OF NEPHROLOGY | 1990年 / 10卷 / 03期
关键词：
D O I：
10.1159/000168078
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Serum soluble interleukin-2 receptor (IL-2R) concentrations were determined using the ELISA method in 55 cases of glomerulonephritis. These patients can be classified as 29 cases of IgA nephropathy, 10 cases of membranous glomerulonephritis and 16 cases of mesangial proliferative glomerulonephritis. Our results showed that serum soluble IL-2R concentrations in glomerulonephritis cases were significantly higher than those in healthy controls. Among the different types of glomerulonephritis cases, however, no significant differences in serum soluble IL-2R were observed. While we found a significant positive correlation of serum soluble IL-2R to BUN and creatinine, we also found a significant negative correlation between serum soluble IL-2R and creatinine clearance. These findings suggest that serum soluble IL-2R can serve as an indicator of exacerbation of glomerulonephritis.
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页码：181 / 185
页数：5
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