DERACEMIZATION OF AXIALLY DISSYMMETRIC COMPOUNDS BY ENANTIOSELECTIVE DEHYDROHALOGENATION USING CHIRAL LITHIUM AMIDES .2.

被引：16
作者：
DUHAMEL, L
RAVARD, A
PLAQUEVENT, JC
机构：
[1] URA D 0464, UFR Sciences et Techniques, Université de Rouen, F 76134 Mont Saint Aignan Cedex
来源：
TETRAHEDRON-ASYMMETRY | 1990年 / 1卷 / 06期
关键词：
D O I：
10.1016/0957-4166(90)90030-E
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
New findings about deracemization of unsaturated carboxylic acids 1 by enantioselective dehydrohalogenation of prochiral species 2 by chiral lithium amides leading to axially dissymmetric compounds with 80% e.e. are reported. The role of the structure of the prochiral hydrochlorinated intermediate is discussed. An example of axial to central chirality transfer is described. (1a → 3). © 1990.
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页码：347 / 350
页数：4
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