Effects of anabolic steroid treatment associated with physical training in adipose tissue of male Wistar rats

被引：5
作者：
Foletto, Marcela de Paiva [1 ]
Ferrari, Fernanda [1 ]
Peres, Sidney Barnabe [1 ]
Franzoi de Moraes, Solange Marta [1 ]
Segatelli, Tania Mara [1 ]
Mareze-da-Costa, Cecilia Edna [1 ]
机构：
[1] Univ Estadual Maringa, Ave Colombo 5790, BR-87020900 Maringa, Parana, Brazil
来源：
ACTA SCIENTIARUM-HEALTH SCIENCES | 2015年 / 37卷 / 01期
关键词：
adipocytes; anabolic agents; body weight; exercise; nandrolone;
D O I：
10.4025/actascihealthsci.v37i1.18614
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Anabolic androgenic-steroids (AAS) include a broad class of synthetic derivatives of testosterone, being nandrolone decanoate the most widely used in sports environment. The aim of this study was to evaluate the metabolic effects of nandrolone decanoate in sedentary and trained adult male rats. We established four experimental groups: sedentary control, sedentary treated, trained control and trained treated. The training had consisted of running on a treadmill for nine weeks. Treated animals received intramuscular injections of nandrolone decanoate (0.5 mg kg(-1)) during the last four weeks of physical training. The training time as the drug used were not sufficient to significantly reduce body weight gain, but caused a significative decrease on diameter of adipocytes and in the amount of adipose tissue stored, as well as decreased the plasma levels of glucose and total cholesterol.
引用
收藏
页码：19 / 24
页数：6
相关论文
共 50 条
  • [31] Effects of high-intensity interval training on adipose tissue lipolysis, inflammation, and metabolomics in aged rats
    Sun, Lei
    Li, Fang-Hui
    Li, Tao
    Min, Zhu
    Yang, Luo-Dan
    Gao, Hao-En
    Wu, Da-Shuai
    Xie, Tian
    PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2020, 472 (02): : 245 - 258
  • [32] The Effects of a Moderate Exercise Program on Knee Osteoarthritis in Male Wistar Rats
    Mohammadi, Mohammad Fallah
    Hajizadeh Moghaddam, Akbar
    Mirkarimpur, Hosein
    IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2013, 16 (05) : 683 - 688
  • [33] Effect of physical exercise and anabolic steroid treatment on spinal motoneurons and surrounding glia of wild-type and ALS mice
    Kassa, Roman M.
    Bonafede, Roberta
    Boschi, Federico
    Bentivoglio, Marina
    Mariotti, Raffaella
    BRAIN RESEARCH, 2017, 1657 : 269 - 278
  • [34] Physical exercise down-regulated locomotor side effects induced by haloperidol treatment in Wistar rats
    Alegre Baptista, Pedro Porto
    de Senna, Priscylla Nunes
    Paim, Mariana Fontoura
    Saur, Lisiani
    Blank, Martina
    do Nascimento, Patricia
    Ilha, Jocemar
    Moreira Vianna, Monica Ryff
    Mestriner, Regis Gemerasca
    Achaval, Matilde
    Xavier, Leder Leal
    PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2013, 104 : 113 - 118
  • [35] Effect of safflower oil (Carthamus tinctorius L.) supplementation in the abdominal adipose tissues and body weight of male Wistar rats undergoing exercise training
    da Silva Perez, Elisangela Martins
    Nunes de Alencar, Nylane Maria
    Tavares de Figueiredo, Ingrid Samantha
    Aragao, Karoline Saboia
    Frota Gaban, Socorro Vanesca
    FOOD CHEMISTRY: MOLECULAR SCIENCES, 2022, 4
  • [36] SWIM TRAINING REVERSES SOME EFFECTS OF NANDROLONE DECANOATE IN WISTAR RATS
    Gomes do Nascimento, Lilian Cristina
    Juliano Eustaquio, Jose Martins
    Mendes, Lais Pereira
    dos Santos, Rodrigo Otavio
    Neto, Octavio Barbosa
    REVISTA BRASILEIRA DE MEDICINA DO ESPORTE, 2021, 27 (02) : 147 - 150
  • [37] Anabolic-androgenic steroid abuse and cognitive impairment: Testosterone IMPAIRS biconditional task performance in male rats
    Wood, Ruth, I
    Serpa, Rebecka O.
    BEHAVIOURAL BRAIN RESEARCH, 2020, 379
  • [38] Timing of exercise differentially impacts adipose tissue gain in male adolescent rats
    Kutsenko, Y.
    Iniguez, L. P.
    Barreda, A.
    Pardo-Marin, L.
    Toval, A.
    Garrigos, D.
    Martinez-Morga, M.
    Pujante, S.
    Do-Couto, B. Ribeiro
    Tseng, K. Y.
    Ceron, J. J.
    Garaulet, M.
    Wisniewska, M. B.
    Irimia, M.
    Ferran, J. L.
    MOLECULAR METABOLISM, 2025, 93
  • [39] Effects of swim training on liver carcinogenesis in male Wistar rats fed a low-fat or high-fat diet
    Aguiar e Silva, Marco Aurelio
    Vechetti-Junior, Ivan Jose
    do Nascimento, Andre Ferreira
    Furtado, Kelly Silva
    Azevedo, Luciana
    Ribeiro, Daniel Araki
    Barbisan, Luis Fernando
    APPLIED PHYSIOLOGY NUTRITION AND METABOLISM, 2012, 37 (06) : 1101 - 1109
  • [40] Effects of Taurine Supplementation on Adipose Tissue of Obese Trained Rats
    de Almeida Martiniano, Ana Carolina
    De Carvalho, Flavia Giolo
    Marchini, Julio Sergio
    Garcia, Sergio Britto
    Elias Junior, Jorge
    Mauad, Fernando Marum
    Ramos da Silva, Adelino Sanchez
    de Moraes, Camila
    de Freitas, Ellen Cristini
    TAURINE 9, 2015, 803 : 707 - 714
12345