MESOSCOPIC MODELING OF WAVE-PROPAGATION IN EXCITABLE MEDIA

被引:5
作者
ITO, H [1 ]
机构
[1] MCGILL UNIV,DEPT PHYSIOL,MONTREAL,PQ,CANADA
来源
PHYSICA D | 1994年 / 79卷 / 01期
关键词
D O I
10.1016/0167-2789(94)90036-1
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
A new theoretical model is introduced to abstract the significant factors leading to wave propagation in excitable media. Contrary to the previous theoretical models constructed based on the microscopic physical mechanism, our model is formulated based on experimentally measurable ''mesoscopic'' characteristics of the media: dispersion relation and curvature relation. Analytic investigations lead to the nonlinear curvature relation which is approximated by a linear relation for a small curvature. Numerical simulations incorporated with the experimental data of the above two characteristics in the Belousov-Zhabotinskii reaction reproduce spiral waves in agreement with experiment. Both stationary rotating spiral waves and a meandering motion of spiral tip are obtained in accord with other experimental and numerical studies. Our results suggest that both the dispersion relation and the curvature relation are important factors leading to those universally observed wave phenomena. The model can be used as a convenient numerical tool to understand the nature of wave propagation in excitable media through extensive numerical experiment.
引用
收藏
页码:16 / 40
页数:25
相关论文
共 61 条
[1]   LINEAR-STABILITY ANALYSIS OF ROTATING SPIRAL WAVES IN EXCITABLE MEDIA [J].
BARKLEY, D .
PHYSICAL REVIEW LETTERS, 1992, 68 (13) :2090-2093
[2]   SPIRAL-WAVE DYNAMICS IN A SIMPLE-MODEL OF EXCITABLE MEDIA - THE TRANSITION FROM SIMPLE TO COMPOUND ROTATION [J].
BARKLEY, D ;
KNESS, M ;
TUCKERMAN, LS .
PHYSICAL REVIEW A, 1990, 42 (04) :2489-2492
[3]   RECONSTRUCTION OF ACTION POTENTIAL OF VENTRICULAR MYOCARDIAL FIBERS [J].
BEELER, GW ;
REUTER, H .
JOURNAL OF PHYSIOLOGY-LONDON, 1977, 268 (01) :177-210
[4]   SPIRAL WAVE SOLUTIONS FOR REACTION DIFFUSION-EQUATIONS IN A FAST REACTION SLOW DIFFUSION LIMIT [J].
BERNOFF, AJ .
PHYSICA D, 1991, 53 (01) :125-150
[5]  
COURTEMANCHE M, IN PRESS CHAOS SOLIT
[6]   RE-ENTRANT ROTATING WAVES IN A BEELER-REUTER BASED MODEL OF TWO-DIMENSIONAL CARDIAC ELECTRICAL ACTIVITY [J].
Courtemanche, Marc ;
Winfree, Arthur T. .
INTERNATIONAL JOURNAL OF BIFURCATION AND CHAOS, 1991, 1 (02) :431-444
[7]   SUSTAINED VORTEX-LIKE WAVES IN NORMAL ISOLATED VENTRICULAR MUSCLE [J].
DAVIDENKO, JM ;
KENT, PF ;
CHIALVO, DR ;
MICHAELS, DC ;
JALIFE, J .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (22) :8785-8789
[8]  
Davydov V. A., 1991, Soviet Physics - Uspekhi, V34, P665, DOI 10.1070/PU1991v034n08ABEH002462
[9]   STABILITY OF VORTEX ROTATION IN AN EXCITABLE CELLULAR MEDIUM [J].
FAST, VG ;
EFIMOV, IR .
PHYSICA D, 1991, 49 (1-2) :75-81
[10]  
FIELD RJ, 1974, J CHEM PHYS, V60, P1877, DOI 10.1063/1.1681288