DO-STAT FED-BATCH PRODUCTION OF CIS,CIS-MUCONIC ACID FROM BENZOIC-ACID BY PSEUDOMONAS-PUTIDA BM014

被引：21

作者：

BANG, SG

CHOI, CY

机构：

[1] SEOUL NATL UNIV,COLL ENGN,INTERDISCIPLINARY PROGRAM BIOCHEM ENGN & BIOTECHN,SEOUL 151742,SOUTH KOREA

[2] SEOUL NATL UNIV,COLL ENGN,DEPT CHEM TECHNOL,SEOUL 151742,SOUTH KOREA

来源：

JOURNAL OF FERMENTATION AND BIOENGINEERING | 1995年 / 79卷 / 04期

关键词：

CIS; CIS-MUCONIC ACID; FED-BATCH PROCESS; PSEUDOMONAS PUTIDA;

D O I：

10.1016/0922-338X(95)94001-8

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

For the production of cis,cis-muconic acid via biocatalytic conversion reactions from a toxic cosubstrate, benzoic acid, we developed a fed-batch process using computer-controlled DO-stat feeding. The mutant strain of Pseudomonas putida BM014 produced cis,cis-muconic acid with high conversion yield. More than 32 g/l of cis,cis-muconic acid was accumulated in 40 h including the initial batch and constant-feeding periods and a productivity value more than 2.2 g/(l . h) was achieved.

引用

页码：381 / 383

页数：3

共 8 条

[1] HIGH CELL-DENSITY CULTURE OF ESCHERICHIA-COLI IN A FED BATCH SYSTEM WITH DISSOLVED-OXYGEN AS SUBSTRATE FEED INDICATOR [J].