ENERGY RESTRICTION AND CARCINOGENESIS

The effects of restricting calorific intake on tumor development and lifespan are discussed. The extent of calorific restriction necessary to decrease tumor incidence and multiplicity were also investigated. Reduced plasma insulin levels, a consequence of calorific intake restriction could be related to tumor growth inhibition. Vigorous exercise, another way of restricting calorific flux, was also found to inhibit tumor growth. Exercise and restricted calorific intake may lead to longer lifespans.