DEVELOPMENT OF ACUTE MYELOCYTIC-LEUKEMIA IN PATIENTS WITH CROHNS-DISEASE

被引：17

作者：

HALME, L ^{[1
]}

VONKNORRING, J ^{[1
]}

ELONEN, E ^{[1
]}

机构：

[1] UNIV HELSINKI, CENT HOSP, DEPT MED 3, SF-00100 HELSINKI 10, FINLAND

来源：

DIGESTIVE DISEASES AND SCIENCES | 1990年 / 35卷 / 12期

关键词：

acute myelocytic leukemia; Crohn's disease;

D O I：

10.1007/BF01540575

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

In our hospital within one year two patients with Crohn's disease were seen who developed an acute myelocytic leukemia. A review of the literature reveals eight previously reported patients with both Crohn's disease and leukemia. Six of the reported 10 patients have had acute myelocytic leukemia and, interestingly, three of them, including our two patients, have shown monocytic differentiation (FAB type M4). It has been suggested that the relative risk of leukemia, especially acute myelocytic leukemia, is increased in patients suffering from ulcerative colitis. More data of patients with Crohn's disease and acute leukemia are needed to evaluate the possible association between these diseases. © 1990 Plenum Publishing Corporation.

引用

页码：1553 / 1556

页数：4

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