SYNTHESIS OF CYCLIC OLIGODEOXYRIBONUCLEOTIDES WITH NON-NUCLEOTIDE INSERTS

被引：0

作者：

ORETSKAYA, TS ^{[1
]}

DOLINNAYA, NG ^{[1
]}

MERENKOVA, IN ^{[1
]}

KRYNETSKAYA, NF ^{[1
]}

ROMANOVA, EA ^{[1
]}

VOLKOV, EM ^{[1
]}

BLUMENFELD, M ^{[1
]}

VASSEUR, M ^{[1
]}

SHABAROVA, ZA ^{[1
]}

机构：

[1] GENSET CORP,PARIS,FRANCE

来源：

BIOORGANICHESKAYA KHIMIYA | 1994年 / 20卷 / 01期

关键词：

D O I：

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学科分类号：

摘要：

An effective method for the oligonucleotide cyclization using BrCN-induced chemical ligation was developed. The novel idea to incorporate non-nucleotide inserts makes the process of cyclizations independent of the inner secondary structure of the linear precursor. An set of assays were developed to confirm the cyclic structure of the compounds obtained.

引用

页码：63 / 66

页数：4

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