CHOLESTEROL CONTENT AND METABOLISM IN NORMAL AND POLYOMA VIRUS-TRANSFORMED HAMSTER EMBRYO FIBROBLASTS

被引：13
作者：
MARKMALCHOFF, D
MARINETTI, GV
HARE, JD
MEISLER, A
机构：
[1] UNIV ROCHESTER,SCH MED & DENT,DEPT MICROBIOL,ROCHESTER,NY 14642
[2] UNIV ROCHESTER,SCH MED & DENT,DEPT MED,ROCHESTER,NY 14642
来源：
EXPERIMENTAL CELL RESEARCH | 1979年 / 118卷 / 02期
关键词：
D O I：
10.1016/0014-4827(79)90161-7
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The total cholesterol content of normal hamster embryo fibroblasts and polyoma virus-transformed hamster embryo fibroblasts were found to be similar. However, the free cholesterol: cholesterol ester ratio was 41.5 in normal cells as contrasted to 1.8 in their transformed counterparts. This difference is due in part to an increase in cholesterol esterification and a decrease in the hydrolysis of cholesterol esters in the transformed cell. © 1979.
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页码：377 / 381
页数：5
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