A MODEL FOR OUTGROWTH OF BRANCHING NEURITES

被引：32

作者：

VANVEEN, M

VANPELT, J

机构：

[1] Netherlands Institute of Brain Research, 1105 AZ Amsterdam

来源：

JOURNAL OF THEORETICAL BIOLOGY | 1992年 / 159卷 / 01期

关键词：

D O I：

10.1016/S0022-5193(05)80764-7

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The outgrowth of branching neurites is studied by modeling the dynamic behavior of the growth cones, which are the active structures at the neuritic tips. The basic actions of the growth cones comprise elongation, branching and guidance as a result of interaction with the local environment. The neurite itself is modeled by an elastic structure. The model is able to reproduce metrical and topological characteristics of tissue-cultured neurites (described by Bray, 1973, J. Cell Biol. 56, 702-712). The model shows that morphological characteristics of neurites can emerge from mechanisms acting purely at the level of the growth cone. © 1992 Academic Press Limited All rights reserved.

引用

页码：1 / 23

页数：23

共 45 条

[1]

[Anonymous], 1986, NUMERICAL RECIPES

[2] APPLICATION OF NETWORK ANALYSIS TO STUDY OF BRANCHING PATTERNS OF LARGE DENDRITIC FIELDS [J].