MODEL STUDIES OF INTERACTIONS BETWEEN NUCLEIC-ACIDS AND PROTEINS - HYDROGEN-BONDING OF AMIDES WITH NUCLEIC-ACID BASES

被引：27
|
作者：
LANCELOT, G
HELENE, C
机构：
[1] Centre de Biophysique Moléculaire
来源：
NUCLEIC ACIDS RESEARCH | 1979年 / 6卷 / 03期
关键词：
D O I：
10.1093/nar/6.3.1063
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The formation of hydrogen bonded complexes between nucleic acid bases and acetamide has been studied by nuclear magnetic resonance in CDCl3 at different temperatures. Pairs of hydrogen bonds are formed when acetamide binds to nucleic acid bases. Thermodynamic parameters have been computed and compared to those obtained for the association of carboxylic acids with nucleic acid bases. The role of hydrogen bonded complexes in the association of proteins with nucleic acids is discussed. © 1979 Information Retrieval Limited.
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页码：1063 / 1072
页数：10
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