NOVEL BIOLOGIC THERAPIES FOR MALIGNANT GLIOMAS - ANTIANGIOGENESIS, IMMUNOTHERAPY, AND GENE-THERAPY

被引:25
作者
FINE, HA
机构
[1] HARVARD UNIV,BRIGHAM & WOMENS HOSP,SCH MED,CTR BRAIN TUMOR,BOSTON,MA 02115
[2] HARVARD UNIV,CHILDRENS HOSP,SCH MED,DANA FARBER CANC INST,BOSTON,MA 02115
[3] HARVARD UNIV,SCH MED,JOINT CTR RADIAT THERAPY,BOSTON,MA 02115
关键词
D O I
10.1016/S0733-8619(18)30020-3
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Despite recent advances in neurosurgical techniques and radiotherapy prognosis remains poor for most patients.;It is becoming increasingly clear that novel treatment strategies are needed. This article explores some of the promising new therapies for malignant gliomas in terms of their biologic principles and preclinical data. Antiangiogenesis, immunotherapy, and gene therapy are discussed.
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页码:827 / &
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