POTENTIAL ANTILEUKEMIC AND IMMUNOSUPPRESSIVE DRUGS .2. FURTHER STUDIES WITH BENZO-2,1,3-OXADIAZOLES (BENZOFURAZANS)AND THEIR N-OXIDES(BENZOFUROXANS)

被引：37

作者：

GHOSH, PB

WHITEHOUSE, MW

机构：

[1] Department of Medical Chemistry, John Curtin School of Medical Research, Australian National University, Canberra, A.C.T.

[2] College of Pharmacy, Ohio State University, Columbus

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1969年 / 12卷 / 03期

关键词：

D O I：

10.1021/jm00303a606

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The synthesis of pyrido[2,3-c]furoxan and some novel amino- and hydroxybenzofurazans is described. The activity of these compounds as inhibitors of protein and nucleic acid biosynthesis in vitro in lymphocytes was determined. © 1969, American Chemical Society. All rights reserved.

引用

页码：505 / +

页数：1

共 14 条

[1] DERIVATIVES OF 2,6-DIAMINOPYRIDINE .2. [J].

BERNSTEIN, J ;

STEARNS, B ;

SHAW, E ;

LOTT, WA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1947, 69 (05) :1151-1158

[2] PYRIDO-2,3-FUROXANE [J].

BOYER, JH ;

MCCANE, DI ;

MCCARVILLE, WJ ;

TWEEDIE, AT .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1953, 75 (21) :5298-5300

[3]

CASONI DDM, 1965, Patent No. 660379

[4]

CASONI DDM, 1965, Patent No. 6510031

[5]

DALMONTE D, 1964, ANN CHIM ITALY, V54, P486

[6]

DALMONTE D, 1963, ANN CHIM ITALY, V53, P1697

[7]

DENHERTOG HJ, 1953, RECL TRAV CHIM PAY B, V72, P125

[8] CONTRIBUTION TO THE CHEMISTRY OF BENZFUROXAN AND BENZFURAZAN DERIVATIVES [J].

GAUGHRAN, RJ ;

PICARD, JP ;

KAUFMAN, JVR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1954, 76 (08) :2233-2236

[9] PREPARATION AND STUDY OF SOME 5- AND 7-SUBSTITUTED 4-NITROBENZOFURAZANS AND THEIR N-OXIDES - A RETRO-BOULTON-KATRITZKY REARRANGEMENT [J].

GHOSH, PB .

JOURNAL OF THE CHEMICAL SOCIETY B-PHYSICAL ORGANIC, 1968, (03) :334-&

[10] POTENTIAL ANTILEUKEMIC AND IMMUNOSUPPRESSIVE DRUGS . PREPARATION AND IN VITRO PHARMACOLOGICAL ACTIVITY OF SOME BENZO-2,1,3-OXADIAZOLES (BENZOFURAZANS) AND THEIR N-OXIDES (BENZOFUROXANS) [J].

GHOSH, PB ;

WHITEHOUSE, MW .

JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (02) :305-+

← 1 2 →